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| 29.10.2025 15:29:50 | 
Press Release: Novartis ianalumab first drug to -2-
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References
1. Thomas GB, Xavier M, Stephanie F et al. Ianalumab demonstrates
significant reduction in disease activity in patients with Sjögren's
Disease: Efficacy and safety results from two global Phase 3, randomized,
placebo-controlled double-blind studies (NEPTUNUS-1 and NEPTUNUS-2).
Presented at the American College of Rheumatology (ACR) Congress; October
24-29, 2025; Chicago, Illinois
2. National Academies of Sciences, Engineering, and Medicine; Health and
Medicine Division; Board on Health Care Services; Committee on Selected
Immune Disorders and Disability. Sjögren's Disease/Syndrome. [Last
accessed: October 2025] https://www.ncbi.nlm.nih.gov/books/NBK584486/
3. Dorner T et al, Safety and Efficacy of ianalumab in patients with
Sjögren's disease: 52-week results from a randomized,
placebo-controlled, Phase 2b dose-ranging study, Arthritis and
Rheumatology 2025, 77(5):560-570
4. Lee AY, Qi Z, Jackson KJ, et al. Self-reactive B cells are increased in
all major stages of peripheral development in Sjögren's disease.
Immunology & Cell Biology 2025; 103: 401-410.
5. Both T, Dalm VA, van Hagen PM, et al. Reviewing primary Sjögren's
syndrome: beyond the dryness - From pathophysiology to diagnosis and
treatment. Int J Med Sci 2017; 14: 191-200.
6. Cornec D, Devauchelle-Pensec V, Tobón GJ, et al. B cells in
Sjögren's syndrome: from pathophysiology to diagnosis and treatment.
J Autoimmun 2012; 39: 161-167.
7. ClinicalTrials.gov NCT05350072
https://clinicaltrials.gov/study/NCT05350072 [Last accessed: October
2025]
8. ClinicalTrials.gov NCT0539214
https://clinicaltrials.gov/study/NCT05349214 [Last accessed: October
2025]
9. ClinicalTrials.gov NCT05985915
https://clinicaltrials.gov/study/NCT05985915 [Last accessed: October
2025]
10. ClinicalTrials.gov NCT05653219
https://clinicaltrials.gov/study/NCT05653219?intr=ianalumab&aggFilters=phase:3&rank=9
[Last accessed: October 2025]
11. ClinicalTrials.gov NCT05639114
https://www.clinicaltrials.gov/study/NCT05639114 [Last accessed: October
2025]
12. ClinicalTrials.gov NCT05126277
https://clinicaltrials.gov/study/NCT05126277 [Last accessed: October
2025]
13. ClinicalTrials.gov NCT05648968
https://clinicaltrials.gov/study/NCT05648968 [Last accessed: October
2025]
14. ClinicalTrials.gov NTC06470048
https://clinicaltrials.gov/study/NCT06470048 [Last accessed: October
2025]
15. Novartis to strengthen oncology pipeline with agreement to acquire
MorphoSys [AG Press release]. [Press release]. Available at: Novartis to
strengthen oncology pipeline with agreement to acquire MorphoSys AG for
EUR 68 per share or an aggregate of EUR 2.7bn in cash | Novartis
https://www.novartis.com/news/media-releases/novartis-strengthen-oncology-pipeline-agreement-acquire-morphosys-ag-eur-68-share-or-aggregate-eur-27bn-cash
[Last accessed: October 2025]
16. Negrini S et al, Sjögren's syndrome: a systemic autoimmune disease,
Clin Exp Med. 2022; 22(1): 9--25
17. Maleki Fischbach-M, et al, Manifestations and management of
Sjögren's disease, Arthritis Res Ther, 2024; 26(1):43
18. Mariette, Primary Sjögren's symptoms, New England Journal of
Medicine, 2018, 378;10
19. Kerry Gairy et al, Burden of illness among subgroups of px with primary
SjD and systemic involvement, Rheumatology 2021, Volume 60, Issue 4,
April 2021, Pages 1871--1881
20. Conrad N, et al, Incidence, prevalence, and co-occurrence of autoimmune
disorders over time and by age, sex, and socioeconomic status: a
population-based cohort study of 22 millions individuals in the UK,
Lancet. 2023;401(10391):1878-1890;
21. Narváez J et al, Prevalence of Sjögren's syndrome in the
general adult population in Spain: estimating the proportion of
undiagnosed cases, Sci Rep. 2020;10(1):10627
# # #
Novartis Media Relations
E-mail: media.relations@novartis.com
Novartis Investor Relations
Central investor relations line: +41 61 324 7944
E-mail: investor.relations@novartis.com
(END) Dow Jones Newswires
October 29, 2025 10:30 ET (14:30 GMT)
Nachrichten zu Novartis AG
| 30.10.25 | Novartis Aktie News: Novartis am Nachmittag gefragt (finanzen.ch) | |
| 30.10.25 | Novartis Aktie News: Novartis am Mittag mit negativen Vorzeichen (finanzen.ch) | |
| 30.10.25 | Novartis Aktie News: Anleger schicken Novartis am Vormittag auf rotes Terrain (finanzen.ch) | |
| 29.10.25 | STOXX-Handel STOXX 50 verliert nachmittags (finanzen.ch) | |
| 29.10.25 | Schwacher Handel: SMI fällt (finanzen.ch) | |
| 29.10.25 | Schwacher Handel: SLI präsentiert sich nachmittags leichter (finanzen.ch) | |
| 29.10.25 | Aktien-Tipp Novartis-Aktie: DZ BANK bewertet Anteilsschein in neuer Analyse (finanzen.ch) | |
| 29.10.25 | Press Release: Novartis ianalumab first drug to -2- (Dow Jones) | 
Analysen zu Novartis AG
| 29.10.25 | Novartis Kaufen | DZ BANK | |
| 29.10.25 | Novartis Buy | Deutsche Bank AG | |
| 29.10.25 | Novartis Neutral | UBS AG | |
| 29.10.25 | Novartis Hold | Jefferies & Company Inc. | |
| 28.10.25 | Novartis Hold | Jefferies & Company Inc. | 
Etienne Jornod (OM Pharma): Führung, Erfolg & Pharma-Strategie- zu Gast im BX Morningcall
Im BX Morning Call spricht die Schweizer Unternehmer-Ikone Etienne Jornod (OM Pharma) mit François Bloch und Olivia Hähnel (BX Swiss) über Führung, Wachstum, Kooperationen, seine Zeit bei der NZZ und darüber, warum Zuhören der wichtigste Leadership-Skill ist.
Die perfekte Folge für alle, die sich für Pharmastrategien, Galenica/Vifor und Unternehmertum interessieren.
🎯 Themen im Interview mit Etienne Jornod (OM Pharma)
– Antrieb und Führungsphilosophie eines Unternehmers
– Erfolgsweg von Galenica – Lehren aus Jahrzehnten Führung
– Frauenquote, Teamkultur und Leadership bei OM Pharma
– Internationale Expansion: China, USA und neue Märkte
– Forschung, Druck und Verantwortung in der Pharmaindustrie
– Inspiration, Balance und persönliche Haltung zum Erfolg
– Zukunftsvisionen: Schweiz, Unternehmertum und Investments
👉🏽 https://bxplus.ch/bx-musterportfolio/
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